target-specific sirnas (Santa Cruz Biotechnology)
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Santa Cruz Biotechnology
target-specific sirnas
Target Specific Sirnas, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/target-specific+sirnas/target+specific+sirnas/pm40499874-76-5-25
Average 90 stars, based on 1 article reviews
Target Specific Sirnas, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/target-specific+sirnas/target+specific+sirnas/pm40499874-76-5-25
Average 90 stars, based on 1 article reviews
target-specific sirnas - by Bioz Stars,
2026-09
90/100 stars
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Knockdown:Article Title: Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X. Article Snippet: Nan Qin, Aguirre A. de Cubas, Ruben Garcia-Martin, Susan Richter, Mirko Peitzsch, Mario Menschikowski, Jacques W.M.. Lenders, Henri J. L. M. Timmers, Massimo Mannelli, Giuseppe Opocher, Matina Economopoulou, Gabriele Siegert, Triantafyllos Chavakis, Karel Pacak, Mercedes Robledo and Graeme Eisenhofer 1 Institute of Clinical Chemistry and Laboratory Medicine, Technische Universit€at Dresden, Dresden, Germany 2 Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO) and ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain 3 Department of Clinical Pathobiochemistry, Technische Universit€at Dresden, Dresden, Germany 4 Medical Clinic III, Technische Universit€at Dresden, Dresden, Germany 5 Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands 6 Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy 7 Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology IRCCS, Padova, Italy 8 Department of Medicine, University of Padova, Padova, Italy 9 Department of Ophthalmology, Technische Universit€at Dresden, Dresden, Germany 10 Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Washington DC, Bethesda, MD Article Title: Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells Article Snippet: 116 117 7 RNAi knockdown of SLFN5 118 Transient knockdown of SLFN5, MMP-1 and MMP-13 was performed using a pool of 119 three target-specific siRNAs as well as Article Title: The siRNA-mediated downregulation of N-Ras sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors. Article Snippet: The clinical benefit of selective BRAF inhibitor therapies is limited by the emergence of drug resistance.. Here, we investigated the molecular basis underlying the acquired resistance to a BRAF inhibitor by comparing the signaling pathways in the parental A375P cells and the resistant subline (A375P/Mdr).. We demonstrate that MAPK re-activation does not contribute to the mechanism of resistance to UAI-201 of A375P/Mdr cells. Article Title: Down-regulation of c-Cbl by Morphine Accounts for Persistent ERK1/2 Signaling in δ-Opioid Receptor-expressing HEK293 Cells Article Snippet: Knockdown of c-Cbl expression was achieved by transfection of HEK/DOR cells with three target-specific Article Title: Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers. Article Snippet: Control siRNA was a pool of four-scrambled Article Title: Apoptosis linked gene-2 interacting protein X as a target to regulate the yield of small extracellular vesicles derived from tissue specific mesenchymal stem cells for translational applications. Article Snippet: Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) have emerged as promising therapeutic agents in regenerative medicine.. However, their clinical translation remains limited by low production yields.. The prime objective of this study was aimed at dissecting the regulatory mechanisms of sEV biogenesis in MSCs by investigating the roles of key proteins involved in both ESCRT-dependent (HRS, STAM, TSG101, ALIX) and ESCRT-independent (RAB27A, RAB27B) pathways. Control:Article Title: Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X. Article Snippet: Nan Qin, Aguirre A. de Cubas, Ruben Garcia-Martin, Susan Richter, Mirko Peitzsch, Mario Menschikowski, Jacques W.M.. Lenders, Henri J. L. M. Timmers, Massimo Mannelli, Giuseppe Opocher, Matina Economopoulou, Gabriele Siegert, Triantafyllos Chavakis, Karel Pacak, Mercedes Robledo and Graeme Eisenhofer 1 Institute of Clinical Chemistry and Laboratory Medicine, Technische Universit€at Dresden, Dresden, Germany 2 Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO) and ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain 3 Department of Clinical Pathobiochemistry, Technische Universit€at Dresden, Dresden, Germany 4 Medical Clinic III, Technische Universit€at Dresden, Dresden, Germany 5 Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands 6 Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy 7 Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology IRCCS, Padova, Italy 8 Department of Medicine, University of Padova, Padova, Italy 9 Department of Ophthalmology, Technische Universit€at Dresden, Dresden, Germany 10 Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Washington DC, Bethesda, MD Article Title: Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells Article Snippet: 116 117 7 RNAi knockdown of SLFN5 118 Transient knockdown of SLFN5, MMP-1 and MMP-13 was performed using a pool of 119 three target-specific siRNAs as well as Article Title: The siRNA-mediated downregulation of N-Ras sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors. Article Snippet: The clinical benefit of selective BRAF inhibitor therapies is limited by the emergence of drug resistance.. Here, we investigated the molecular basis underlying the acquired resistance to a BRAF inhibitor by comparing the signaling pathways in the parental A375P cells and the resistant subline (A375P/Mdr).. We demonstrate that MAPK re-activation does not contribute to the mechanism of resistance to UAI-201 of A375P/Mdr cells. Article Title: Down-regulation of c-Cbl by Morphine Accounts for Persistent ERK1/2 Signaling in δ-Opioid Receptor-expressing HEK293 Cells Article Snippet: Knockdown of c-Cbl expression was achieved by transfection of HEK/DOR cells with three target-specific Article Title: Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers. Article Snippet: Control siRNA was a pool of four-scrambled Article Title: Apoptosis linked gene-2 interacting protein X as a target to regulate the yield of small extracellular vesicles derived from tissue specific mesenchymal stem cells for translational applications. Article Snippet: Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) have emerged as promising therapeutic agents in regenerative medicine.. However, their clinical translation remains limited by low production yields.. The prime objective of this study was aimed at dissecting the regulatory mechanisms of sEV biogenesis in MSCs by investigating the roles of key proteins involved in both ESCRT-dependent (HRS, STAM, TSG101, ALIX) and ESCRT-independent (RAB27A, RAB27B) pathways. Expressing:Article Title: Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X. Article Snippet: Nan Qin, Aguirre A. de Cubas, Ruben Garcia-Martin, Susan Richter, Mirko Peitzsch, Mario Menschikowski, Jacques W.M.. Lenders, Henri J. L. M. Timmers, Massimo Mannelli, Giuseppe Opocher, Matina Economopoulou, Gabriele Siegert, Triantafyllos Chavakis, Karel Pacak, Mercedes Robledo and Graeme Eisenhofer 1 Institute of Clinical Chemistry and Laboratory Medicine, Technische Universit€at Dresden, Dresden, Germany 2 Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO) and ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain 3 Department of Clinical Pathobiochemistry, Technische Universit€at Dresden, Dresden, Germany 4 Medical Clinic III, Technische Universit€at Dresden, Dresden, Germany 5 Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands 6 Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy 7 Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology IRCCS, Padova, Italy 8 Department of Medicine, University of Padova, Padova, Italy 9 Department of Ophthalmology, Technische Universit€at Dresden, Dresden, Germany 10 Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Washington DC, Bethesda, MD Article Title: Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells Article Snippet: 116 117 7 RNAi knockdown of SLFN5 118 Transient knockdown of SLFN5, MMP-1 and MMP-13 was performed using a pool of 119 three target-specific siRNAs as well as Article Title: The siRNA-mediated downregulation of N-Ras sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors. Article Snippet: The clinical benefit of selective BRAF inhibitor therapies is limited by the emergence of drug resistance.. Here, we investigated the molecular basis underlying the acquired resistance to a BRAF inhibitor by comparing the signaling pathways in the parental A375P cells and the resistant subline (A375P/Mdr).. We demonstrate that MAPK re-activation does not contribute to the mechanism of resistance to UAI-201 of A375P/Mdr cells. Article Title: Down-regulation of c-Cbl by Morphine Accounts for Persistent ERK1/2 Signaling in δ-Opioid Receptor-expressing HEK293 Cells Article Snippet: Knockdown of c-Cbl expression was achieved by transfection of HEK/DOR cells with three target-specific Article Title: Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers. Article Snippet: Control siRNA was a pool of four-scrambled Article Title: Apoptosis linked gene-2 interacting protein X as a target to regulate the yield of small extracellular vesicles derived from tissue specific mesenchymal stem cells for translational applications. Article Snippet: Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) have emerged as promising therapeutic agents in regenerative medicine.. However, their clinical translation remains limited by low production yields.. The prime objective of this study was aimed at dissecting the regulatory mechanisms of sEV biogenesis in MSCs by investigating the roles of key proteins involved in both ESCRT-dependent (HRS, STAM, TSG101, ALIX) and ESCRT-independent (RAB27A, RAB27B) pathways. Transfection:Article Title: Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X. Article Snippet: Nan Qin, Aguirre A. de Cubas, Ruben Garcia-Martin, Susan Richter, Mirko Peitzsch, Mario Menschikowski, Jacques W.M.. Lenders, Henri J. L. M. Timmers, Massimo Mannelli, Giuseppe Opocher, Matina Economopoulou, Gabriele Siegert, Triantafyllos Chavakis, Karel Pacak, Mercedes Robledo and Graeme Eisenhofer 1 Institute of Clinical Chemistry and Laboratory Medicine, Technische Universit€at Dresden, Dresden, Germany 2 Hereditary Endocrine Cancer Group, Spanish National Cancer Research Centre (CNIO) and ISCIII Center for Biomedical Research on Rare Diseases (CIBERER), Madrid, Spain 3 Department of Clinical Pathobiochemistry, Technische Universit€at Dresden, Dresden, Germany 4 Medical Clinic III, Technische Universit€at Dresden, Dresden, Germany 5 Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands 6 Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy 7 Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology IRCCS, Padova, Italy 8 Department of Medicine, University of Padova, Padova, Italy 9 Department of Ophthalmology, Technische Universit€at Dresden, Dresden, Germany 10 Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Washington DC, Bethesda, MD Article Title: Human Schlafen 5 (SLFN5) Is a Regulator of Motility and Invasiveness of Renal Cell Carcinoma Cells Article Snippet: 116 117 7 RNAi knockdown of SLFN5 118 Transient knockdown of SLFN5, MMP-1 and MMP-13 was performed using a pool of 119 three target-specific siRNAs as well as Article Title: The siRNA-mediated downregulation of N-Ras sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors. Article Snippet: The clinical benefit of selective BRAF inhibitor therapies is limited by the emergence of drug resistance.. Here, we investigated the molecular basis underlying the acquired resistance to a BRAF inhibitor by comparing the signaling pathways in the parental A375P cells and the resistant subline (A375P/Mdr).. We demonstrate that MAPK re-activation does not contribute to the mechanism of resistance to UAI-201 of A375P/Mdr cells. Article Title: Down-regulation of c-Cbl by Morphine Accounts for Persistent ERK1/2 Signaling in δ-Opioid Receptor-expressing HEK293 Cells Article Snippet: Knockdown of c-Cbl expression was achieved by transfection of HEK/DOR cells with three target-specific Article Title: Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers. Article Snippet: Control siRNA was a pool of four-scrambled Article Title: Apoptosis linked gene-2 interacting protein X as a target to regulate the yield of small extracellular vesicles derived from tissue specific mesenchymal stem cells for translational applications. Article Snippet: Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) have emerged as promising therapeutic agents in regenerative medicine.. However, their clinical translation remains limited by low production yields.. The prime objective of this study was aimed at dissecting the regulatory mechanisms of sEV biogenesis in MSCs by investigating the roles of key proteins involved in both ESCRT-dependent (HRS, STAM, TSG101, ALIX) and ESCRT-independent (RAB27A, RAB27B) pathways. |
